Discover CBG

Discover CBG

May 08, 2020


Cannabigerol (CBG), is often referred to as the parent molecule or mother cannabinoid to THC, CBD, and other cannabinoids.

Let’s dig deeper and discover, how is it different from Cannabidiol (CBD)? Will it create a “high” like Tetrahydrocannabinol (THC)? Is it safe? These are frequent questions that come up when someone ventures into the hemp/cannabis space. Let’s go over the basics to start and then get more specific.

Here is a basic overview of the endocannabinoid system from an article, by Crystal Raypole.

“The endocannabinoid system (ECS) is a complex cell-signaling system identified in the early 1990s by researchers exploring THC, a well-known cannabinoid. Cannabinoids are compounds found most abundantly in cannabis. Experts are still trying to fully understand the ECS. But so far, we know it plays role in regulating a range of functions and processes, including:

  • sleep
  • mood
  • appetite
  • memory
  • reproduction and fertility

The ECS exists and is active in your body even if you don’t use cannabis.”

We all have an ECS system in our body that is active and produces its own form of endocannabinoids. Those that use cannabis/hemp products are supplementing their body with additional cannabinoids found in cannabinoid-rich hemp oil, just like taking a daily vitamin or supplement.

CBD & CBG are two of 140+ cannabinoids in the cannabis/hemp plant that have been naturally occurring for millions of years. It is only recently that scientists have confirmed scientifically that both the endocannabinoid system and the fact that plant cannabinoids or phyto-cannabinoids can help humans.

There are books and studies being conducted that show that humans are deficient in cannabinoids. The result of this may be why we as humans are frequently sick and suffer from diseases that are caused by inflammation. Since CBD and other cannabinoids can be anti-inflammatory we recommend daily supplementation with hemp oil rich in cannabinoids.

Here are some good quotes from and medical professionals interviewed about CBG:

 “…we have now available CBG (cannabigerol) which is another cannabinoid that has medicinal value – so it’s an analgesic, anti-inflammatory, anti-depressant, it’s a bone stimulant, it’s anti-cancer proliferation. And I’ve been using CBG just about in the past year or so, maybe a little bit longer, in patients who have depression, who do not find benefits with CBD or THC. Also, a large number of my patients (I take care of a lot of children) who have autism are finding that CBG works very nicely for anxiety. So we’ve done some polling with a nonprofit and they’re reporting the number one benefit for CBG in children with autism is less anxiety. And that’s a big, big problem for most people who suffer with autism. We’re also using THCA.”

“…it does have a strong anti-anxiety effect and for people who have had access to it, this is an almost universal describer of the effects. Beyond that, it seems to be a powerful antibiotic that can work on bacteria that are normally resistant to antibiotics, especially Methicillin-resistant Staphylococcus aureus, which has caused some hospital-acquired infections.”

What is CBG?

"CBG is the precursor to CBD, CBC, and THC," says Dr. Solomon. It's sometimes referred to as the stem cell. What does this mean? "CBGa (the acidic, inactive form of CBG) changes, is broken down, and becomes the base molecule that other cannabinoids form from," including THC, CBD, and CBC.

CBG is where it all starts and the cannabinoids in a cannabis/hemp plant are derived or can be traced back to CBGa. This means that individual cannabinoids may have different effects and may be better for X symptom or Y relief, yet they all share some commonality.

Here are some of the specific things CBG may help in a more direct way than some other cannabinoids. This is taken from an article by Dominique Astorino

  • May treat glaucoma and relieve intraocular pressure. This could be a huge deal because CBD on its own does not help with glaucoma, but THC does-so for patients who want to treat glaucoma using cannabis, this may be a way to do so without the intoxication effect. A 1990 study looked at the use of CBG for glaucoma and found that "cannabigerol and related cannabinoids may have therapeutic potential for the treatment of glaucoma." However, you should continue to take doctor-prescribed glaucoma medication, and only take CBG or cannabis as an addition to your Rx meds and after consulting your doctor, says Dr. Solomon.
  • Have antibacterial properties, particularly for MRSA. Methicillin-resistant Staphylococcus aureus or "MRSA" is a type of staph infection that is resistant to methicillin (a common type of antibiotic), rendering it a particularly threatening or even fatal bacterial infection. In a 2008 study, CBG showed promise for treating MRSA as an antibacterial agent. Dr. Solomon said this is an area where CBG shows real promise. "It's thought to help with MRSA," he said. "CBG has potential to treat bacteria that are resistant to traditional antibiotics."
  • Contributes to GABA reuptake inhibition. CBG inhibits GABA uptake, which could lead to muscle relaxation, tension relief, and sensation of calm and peace in the body and brain, according to Bonni Goldstein, M.D., a physician with a distinguished background in pediatrics and a current specialty in cannabis medicine, as she noted in a recent video. A 1975 study corroborated this. Pharmacologically, GABA uptake inhibitors are already used to treat anxiety. Dr. Solomon adds that because of this decreased "GABA uptake," CBG could "potentially decrease anxiety."
  • Could help inflammatory bowel disease and colitis. Rats were studied in 2013 for the use of CBG for colitis, and the results were positive, concluding that CBG reduced the effect of colitis. According to the study, IBD patients have been experiencing "successful management of abdominal pain, joint pain, cramping, diarrhea, poor appetite, weight loss, and nausea" with the use of cannabis, but there are not many studies just yet exploring CBG as an isolated compound.
  • May work for Huntington's and neurodegenerative diseases. A 2015 study on mice found that "the use of CBG, alone or in combination with other phytocannabinoids or therapies, [could be a] treatment of neurodegenerative diseases," such as Huntington's disease. "CBG normalized expression of abnormal genes linked to brain degeneration, showing that it’s a neuroprotective compound," says Dr. Goldstein to Shape.
  • Potentially fights cancer. "CBG is also proven in laboratory studies to inhibit the growth of certain cancer cells," says Dr. Goldstein. A review article in 2009 showed that CBG could potentially slow tumor growth. Another study from 2016 concluded that "the preclinical data strongly support the notion that non-psychoactive plant-derived cannabinoids, [including CBG] can act as direct inhibitors of tumor progression as well as enhance the activity of first-line therapies." A 2014 study found similar results, reporting that CBG inhibited tumor growth in colon cancer, and 2006 study including cannabigerol noted it may help with breast cancer. In 2016, it was shown to be an appetite stimulant in rats, which could help patients undergoing chemotherapy.
  • Showing major promise for inflammation, including of the skin. A 2007 study looked at CBG's ability to treat eczema and psoriasis, and as mentioned, it may help reduce the inflammation caused by IBD.

To get more than just a trace amount of CBG and a broader entourage effect try Kurativ CBD/CBG 10:1 oil. It is a great way to get the benefits of both CBD & CBG. It is 100% USA made with all-natural ingredients, third party lab tested and made in small batches. It is available in both full-spectrum and in an isolate (zero THC) base.

Check with your doctor before adding any medication or supplement-OTC, natural, or otherwise-to your regimen.

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